1) Yes.
2) Likely something is poorly grounded in the audio path: This means the shielding of the audio cables (or wires internally), somewhere in the audio path, is cut or loose. Yes, it is also possible that the shield is OK but you just happen to run the cable parallel to AC wires for some really big electrical equipment.
To test #2, purchase two little female-to-female RCA connectors, and take the sub out of the circuit without moving anything. (Alternatively, unplugging the sub's AC power -- since its RCA connectors are simple pass-thru, no filters or anything -- should be the same test, unless you have some noisy piece of electrical equipment right near it.) I.e. "differential diagnosis": is the hum with the cables, but without the sub, still there?
3) I would say "no that's not normal" but I don't own 18s to know how immune they are to electrical noise. The easiest way to know for sure is to go to your dealer on a quiet afternoon and listen to theirs. Despite having spent a lot of time on setup, theirs will be an electrically-noisy environment with all the gear, so whatever they have for noise should be the upper limit on what you should expect at home.
To test #3, purchase two little RCA "grounding" or "shorting" plugs (or make your own) which are just a wire from the signal pin to the shield. Plug 'em in to the 18s -- after triggering the line-in power-on of course -- and see if the little buzz goes away. Again, differential diagnosis: is it the speakers (their amp board, actually) or the cables (or their source) causing it?
P.S. That Gallo sub has the lowest W.A.F. of any I have ever seen -- even worse than the cylindrical columns from SVS! 😁 So I can see why you might have run extra-long cables to keep it well out of the way! Longer cables pick up more noise, of course, if there is any in the first place. But if the Gallo sub is responsible for the hum (#2), it is possible that the internal wires are un-shielded and its power supply transformer is radiating right beside them; this would be an engineering failure. More likely would be a manufacturing glitch; connections to the outside world are still done by hand many places. An easy fix is to put Y-connectors right at the L/R RCA jacks on the Sonos, and run *separate* cables to the sub and to the 18s, not using the Gallo pass-thru jacks. That doesn't prevent radiating the 60 Hz hum back down the cable, all the way out to the speakers, but so much noise would have to be a truly egregious fault (and cause for a return).