I've never had any trouble with the sound jumping up or down when I adjust the volume. Quite ingeniously, the loudspeakers adjust by exactly 1dB with each press of the up or down arrow on my Beo4.
One tip, since in s/pdif coax mode you won't have the powerlink control of the speakers and the synchronisation cable doesn't do much that I've noticed: run the speakers all the way down to silent. You'll know when they bottom out by watching the green indicator lights. Go down press by press on the volume control, until you are bottomed out.
Then move up until you have a listening level you are comfortable with. Store this level with A.SETUP using LIST.
Should the speakers drift for any reason, as you're adjusting the volume (could be that both don't pick up a command with the Beo4), then you can reset to this preset volume level, and you'll know both speakers are at the same level.
I have different units connected to the Powerlink and s/pdif IN connectors on my BL5s, and haven't had any trouble with that.
Some of the "sound improvement" many tout after having heard the s/pdif connection version of a soundtrack is due to a marked increase in signal output level from the speakers. When you match the corresponding signal output level through Powerlink, to be at the same listening level as the s/pdif, you'll find that the two versions are not as unlike.
However, feeding the s/pdif straight to the BL5s is an advantage, due to their special signal path - the signal is spared at least one conversion.