I personally wouldn't say PowerLink is a 'no-go' with BeoLab 5s, it's just that connecting them to a bit-perfect output produces a notably better sound and means you don't have to rely on any of the circuitry in the source!
Just one thing to check, make sure you're running your MacMini at 44.1 kHz/16 bit (in Audio MIDI Setup in the Applications/Utilities folder). if not, the MacMini will not produce a bit-perfect output (ie, the signal coming out of the digital connection will not be identical to the information from the CD).
Alex, I can partly agree with you about the powerlink, in some cases it's the only available option, but to me it makes no sense to have a 18.000 euro speaker hooked up trough Powerlink instead of SPDIF. The difference is after all unbelievable!
Thanks for the heads up about the bits, but as I said I had help from Soundproof, and he did not miss this part, and made sure I get it right. So the output is 44.1 / 16