You are not the only one who have experienced problems with no sound after the latest update, I got the same problem, ending up making a factory reset of the sound center.
Afterwards I find out that the problem was related to “Clip Protection” a function which is turned ON by default, but in my case turned OFF because I have recognized it cut off the lower bass to my BL5 speakers.
But after this software update it is no longer possible to disable the function, if doing so it will replace the sound with a high frequency tone, which will not disappear before turning the function back ON again and restart the TV.
I lately also has experienced, several times the remote has lost the communication to the TV and need to be re paired, sometimes it’s necessary to make a factory reset to the Beoremote before it is possible to successfully pair the two.
I already has contacted my B&O dealer and even B&O too, so just hope they very soon will come up with a solution.